PASSIVE IMMUNITY TO POLIOMYELITIS IN THE CHIMPANZEE
نویسندگان
چکیده
منابع مشابه
Passive Immunity to Poliomyelitis in the Chimpanzee
A series of 6 chimpanzees was inoculated orally with stool from a poliomyelitis patient. Three of these animals had been given 170 cc. of homologous, hyperimmune monkey serum prior to inoculation, while three were unprotected. All 6 of the animals were subsequently shown to have poliomyelitis virus in their stools and characteristic lesions in their central nervous systems although none of them...
متن کاملNon-paralytic Poliomyelitis in the Chimpanzee
1. Thirteen cases of non-paralytic poliomyelitis infection in chimpanzees are described. Nine of these animals were excreting virus in. their stools at periods of from 3 days to 8 weeks following inoculation. 2. All animals killed during the acute stage showed lesions in the brain distributed in centers usually involved in, and compatible with the presence of, poliomyelitic infection. In 2 chim...
متن کاملPoliomyelitis by Accidental Contagion in the Chimpanzee
Poliomyelitis virus was isolated from the stools of two uninoculated chimpanzees which had been quartered for 6 months in cages adjoining those of rhesus monkeys receiving intranasal inoculations of potent human stools. Upon arrival, and for 4 months thereafter, neither chimpanzee had antibody against the virus eventually isolated from it. However, antibody had developed against the animals' ow...
متن کاملActive Immunity to Poliomyelitis in Chimpanzees following Subclinical Infection
This report is concerned with the production of subclinical poliomyelitis in the chimpanzee, and immunity to such infection. Subclinical infection was produced in eight chimpanzees by the administration of virus orally or intracutaneously, and was measured by the production of a virus carrier state and the development of neutralizing antibodies. Immunity was tested by attempting to induce the c...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1945
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.81.3.247